Tissue Repair and Regeneration Using Stem Cell

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Amyotrophic Lateral Sclerosis is colloquially known as Lou Gehrigs disease which was actually named after one of the famous and best baseball players was treated with it. It is a neurological disease that causes the weakening of the muscles impacting to the physical functions due to nervous cells obliteration (Malik, et al., 2014). The disease is well known to cause annihilations on the muscles, and due to its lack of cure, it slowly twists the muscles and eventually cause destroys the motor neurons causing death to victims. The motor neurons are the nerve cells positioned on the spinal cord, brain stem that controls the communication links between the voluntary body muscles and the nervous system.

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The disease has caused lots of despair hence the scientist has been working on various researches on their trial to find the real cause of ALS, its symptoms and the appropriate cure. No satisfactory cure and prevention has been arrived at but lots of studies have been conducted focusing on the appropriate model that can be adopted in treating Amyotrophic Lateral Sclerosis disease.

Based on researches successfully tested between embryonic and adult stem cells, stem cells have been capacitated as specialized cells with the development of special tissues or organs due to its unlimited cycles in cells. Since Amyotrophic Lateral Sclerosis has no cure, stem cells can be used to reduce its progression. The disease grows and leads to difficulties in talking. This is characterized by sparring while speaking, and walking difficulties through other nervous muscles. However, stem cell is proposed to be an effective mechanism of preventing fast spread of Lou Gehrigs disease (Turner, et. al., 2013). The disease is understood to cause damage to motor neurons which are tasked to control links between the voluntary body muscles and the nervous system, hence, destroying the responsive cells. Stem cells are capable of being any type of a cell in the body. This scientific method, if considered, can prolong the lifespan of the ALS victims. Familial versus sporadic ALS is a research tested in an attempt to understand the common sporadic way of the ALS; hence, some researchers believe that some Familial Amyotrophic Lateral Sclerosis genes can be involved in sporadic ALS. This decision was arrived at as a result that the Familial ALS is virtually inclined and resembles sporadic ALS (Boulis, et al., 2012).

However, since stem cells have the capability of adjusting to any other type of cell, it is possible to convert them into motor neurons and the associate cells that cause Amyotrophic Lateral Sclerosis disease. It is, however, worth funding the research on the replication and emulation of the ALS through stem cell model over the Familial versus Sporadic ALS. The Lou Gehrigs disease will be controlled.


Boulis, N. M., Federici, T., Glass, J. D., Lunn, J. S., Sakowski, S. A., & Feldman, E. L. (2012). Translational stem cell therapy for amyotrophic lateral sclerosis. Nature Reviews Neurology, 8(3), 172-176.

Malik, R., Lui, A., & Lomen-Hoerth, C. (2014, November). Amyotrophic lateral sclerosis. In Seminars in neurology (Vol. 34, No. 05, pp. 534-541). Thieme Medical Publishers.Turner, M. R., Hardiman, O., Benatar, M., Brooks, B. R., Chio, A., De Carvalho, M., ... & Nicholson, G. (2013). Controversies and priorities in amyotrophic lateral sclerosis. The Lancet Neurology, 12(3), 310-322.

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